ISAMM » Experimental Biology » Anti-aging Theories Part II
Anti-aging Theories Part II
Article by Connie Limon
Waste Accumulation Theory
The waste accumulation theory of aging states that in the course of a life span cells create more waste than they can properly remove. The waste consists of a variety of toxins that when accumulated to a particular level they can interfere with typical cell function and ultimately kill the cell.
Limited Number of Cell Divisions Theory
This theory is concerned with the number of cell divisions directly affected by the accumulations of the cell’s waster products. As far more wastes accumulate over time the cells rapidly degenerate thus causing aging and ultimately death.
Hayflick Limit Theory
Dr. Hayflick theorized that the aging method was controlled by a biological clock contained within every living cell. Studies completed in 1961 concluded that human fibroblast cells (lung, skin, muscle, heart) have a limited life span. They divide approximately 50 times over a period of years and then suddenly stop. They also concluded nutrition seemed to have an effect on the rate of cell division. Final conclusion of this theory states that improper functioning of cells and loss of cells in organs and tissues may be responsible for the effects of aging.
Death Hormone Theory (DECO)
Brain cells or neurons are in contrast to other cells in that they do not replicate. At birth we have roughly 12 billion of them and over a life time about 10 percent die out. Dr. Donner Denckle speculated that as we age the pituitary begins to release DECO which inhibits the capability of cells to use thyroxine. Thyrozine is a hormone produced by the thyroid-governing basal metabolism, which is the rate at which cells convert food to energy. The metabolic rate brings on and accelerates the procedure of aging.
Thymic-Stimulating Theory
Dr. Alan Goldstein says “the thymus is the master gland of the immune systems.” The size of the gland continues to minimize and shrink to round three grams by age 60. Scientists are investigating the possibility that the disappearance of the thymus contributes to the aging process by weakening the body’s immune system.
Mitochondrial Theory
This is the totally free radical theory is supported by directed experimental observations of Mitochondrial aging. Our primary source of energy comes from ATP. Mitochondria are the energy-producing organelles in the cells that produce ATP. They create cell energy by a procedure that leads to forming potentially damaging free of charge radicals. Evidence appears to tell us that various kinds of accumulated DNA harm over time contribute to disease. New investigation in mitochondrial repair could play an crucial role in the fight against aging.
Errors and Repairs Theory
Dr. Leslie Orgel suggested in 1963 that because the “machinery for creating protein in cells is so vital, an error in that machinery could be catastrophic.” Because the system is incapable of constantly creating perfect repairs on these molecules, the accumulation of flawed molecules can trigger illness and other age changes to occur.
Redundant DNA Theory
This theory is comparable to the error-and-repairs theory in that it also blames errors accumulating in genes for age adjustments. A distinction is that as these errors accumulate the reserve genetic sequences of identical DNA that take over until the system is work out.
Source: The American Academy of Anti-Aging Medicine
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The details in this write-up is not intended to diagnose, treat, cure or stop any illness. All health concerns need to be addressed by a qualified wellness care professional.
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© 2007 Connie Limon All Rights Reserved
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Connie Limon. Go to http://smalldogs2.com/Anti-AgingArticles for an extensive list of Free of charge reprint articles all about anti-aging. Visit Camelot Articles at http://www.camelotarticles.com







