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ISAMM » Experimental Biology » Anti-aging Theories Part II

Anti-aging Theories Part II


Waste Accumulation Theory

The waste accumulation theory of aging states that in the course of a life span cells create a lot more waste than they can appropriately get rid of.  The waste includes numerous toxins that when accumulated to a specific level they can interfere with typical cell function and ultimately kill the cell.

Limited Number of Cell Divisions Theory

This theory is concerned with the number of cell divisions directly affected by the accumulations of the cell’s waster products.  As a lot more wastes accumulate over time the cells speedily degenerate thus causing aging and ultimately death.

Hayflick Limit Theory

Dr. Hayflick theorized that the aging method was controlled by a biological clock contained inside every living cell.   Studies completed in 1961 concluded that human fibroblast cells (lung, skin, muscle, heart) have a limited life span.  They divide approximately 50 times over a period of years and then suddenly stop.  They also concluded nutrition seemed to have an effect on the rate of cell division.  Final conclusion of this theory states that improper functioning of cells and loss of cells in organs and tissues might be responsible for the effects of aging.

Death Hormone Theory (DECO)

Brain cells or neurons are unlike other cells in that they do not replicate.  At birth we have roughly 12 billion of them and over a life time about 10 percent die out.  Dr. Donner Denckle speculated that as we age the pituitary begins to release DECO which inhibits the capacity of cells to use thyroxine.  Thyrozine is a hormone produced by the thyroid-governing basal metabolism, which is the rate at which cells convert food to energy.  The metabolic rate brings on and accelerates the process of aging.

Thymic-Stimulating Theory

Dr. Alan Goldstein says “the thymus is the master gland of the immune systems.”  The size of the gland continues to lessen and shrink to round 3 grams by age 60.  Scientists are investigating the possibility that the disappearance of the thymus contributes to the aging procedure by weakening the body’s immune system.

Mitochondrial Theory

This is the free radical theory is supported by directed experimental observations of Mitochondrial aging.  Our primary source of energy comes from ATP.  Mitochondria are the energy-producing organelles in the cells that produce ATP.   They create cell energy by a procedure that leads to forming potentially damaging free of charge radicals.  Evidence seems to tell us that numerous kinds of accumulated DNA harm over time contribute to disease.  New study in mitochondrial repair could play an critical role in the fight against aging.

Errors and Repairs Theory

Dr. Leslie Orgel suggested in 1963 that simply because the “machinery for creating protein in cells is so important, an error in that machinery could be catastrophic.”  Given that the system is incapable of always generating excellent repairs on these molecules, the accumulation of flawed molecules can trigger disease and other age adjustments to happen.

Redundant DNA Theory

This theory is comparable to the error-and-repairs theory in that it also blames errors accumulating in genes for age modifications.  A difference is that as these errors accumulate the reserve genetic sequences of identical DNA that take over until the system is work out.

Source:  The American Academy of Anti-Aging Medicine

Disclaimer:  These statements have not been evaluated by the Food and Drug Administration.  The data in this write-up is not intended to diagnose, treat, cure or avoid any illness.  All wellness concerns need to be addressed by a qualified wellness care professional.